Dr. Abraham, who was not involved in this research, continued: “There can be multiple reasons for this, including side effects. It is interesting to see that this real-world data shows worse outcomes in patients with hot flashes, likely leading to more early discontinuation of endocrine therapy. It is important for the clinicians to continue to pay attention to the management of side effects and adherence to therapy.”
The study authors did caution that this research took place in a country with a unified healthcare system, potentially complicating generalizations that can be made to the United States.
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